We are a research group based at UBC-Vancouver working on bioanalytical tools and methods for precise and quantitative interrogation of biological systems.
Rationale & Projects
Life is fundamentally characterized by order, with an orchestra of biochemical reactions running in the compartments within, on and between cells. These reactions have to occur at the right place and at the right time so as to manifest healthy functioning. We work on new methodologies with the aim to provide greater insight into such interactions at different length and time-scales. A particular focus currently is on precise tumor profiling.
open space microfluidics
Reconfigurable microfluidics
Surface assays
Tumor profiling
Featured Articles
Biopatterning
I. Pereiro et al., Biopatterning: The Art of Patterning Biomolecules on Surfaces, Langmuir, 2021.
WellProbe
I. Pereiro et al., Advection-enhanced kinetics in microtiter plates for improved surface assay quantitation and multiplexing capabilities, Angewandte Chemie, 2021.
Mapping Spatial Genetic Landscapes
L. Voith von Voithenberg, A. Kashyap, et al., Mapping Spatial Genetic Landscapes in Tissue Sections through Microscale Integration of Sampling Methodology into Genomic Workflows, Small , 2021.
Micro-scale technologies propel biology
I. Pereiro, J. Aubert, and G. V. Kaigala., Micro-scale technologies propel biology and medicine, Biomicrofluidics , 2021.
Biointegrated Fluidic Milling
D. Widerker, F. Paratore, M. Bercovici., and G. V. Kaigala, Biointegrated Fluidic Milling, Advanced Materials Technologies , 2021.
Rapid microIHC
R. Lovchik, D. Taylor, and G. V. Kaigala, Rapid micro-immunohistochemistry, Microsystems & Nanoengineering , 2020.
Collaborations
We work with several academia and industrial partners in collaborative projects. Much of our collaborations so far have been centered around Europe (ETH-Z, EPFL, Institute Curie, Technion, University Hospital Zurich, Bern and Frankfurt). With the lab moving to Vancouver, we are super excited to work and establish collaborations with colleagues at UBC, Vancouver Coastal Health Research Institute and the BC Cancer Research Institute.